Yinchen is a kind of plant, which is the dry part of the plant. It is harvested in spring and autumn. It can be used after removing the old stems and impurities. The spring yin is called Mian Yinchen, and the autumn yin is called Yinchenhao. The effect of clearing away heat and dampness on the treatment of jaundice hepatitis, the following is a small series for everyone to introduce the efficacy and role of Yinchen.
The effect of Yinchen:
Clearing heat and dampness; retreating yellow. Indications: jaundice; urination is unfavorable; wet sore itching, etc. Pharmacological research is beneficial to protect the liver function, antipyretic, anti-inflammatory, hypolipidemic, antihypertensive, crown expansion, etc. Of course, this is only Western medicine extracts the composition of the ingredients of Yinchen, and the effect on clinical application is not good. Chen Su toxicity is central inhibition, which is characterized by sleepiness, runny nose, etc. Excessive dosage of Yinchen can cause dizziness, nausea, diarrhea, upper abdominal discomfort, acute hepatobiliary injury, and arrhythmia. However, the therapeutic dose of Yinchen Generally do not cause serious damage.
The role of Yinchen:
Yinchen has significant liver-protecting effect. It has significant curative effect on hepatitis A, hepatitis B and jaundice hepatitis. It is beneficial to gallbladder, promotes bile secretion, and increases the secretion of bile acid and bilirubin in bile. It can increase the coronary heart. Blood flow, improve microcirculation, and lower blood pressure, lower blood fat, anticoagulation, diuretic antipyretic, antitussive, repelling aphids and inhibiting the action of a variety of pathogenic skin fungi and bacteria.
1, choleretic effect
Yinchen decoction, Yinchenzhizi decoction, Yinchenhao decoction (Yinchen, medlar, rhubarb to 3:1.5:1) and its alcohol extract all promote the bile secretion of rats, but not obvious enough. Yinchen decoction showed only a slight reduction in gallbladder contraction (X-ray examination) in normal people, and the volume change was not significant.
Yinchen's aqueous extract and refined concentrated infusion (both removed and not removed) have obvious choleretic effects on acute gallbladder intubation and chronic gallbladder fistula. It is speculated that the active ingredients may be water and alcohol-soluble substances. The role of volatile sleeves is questionable or weak; however, it has also been reported that the volatile oil isolated from Nanjing Yinchen has a beneficial effect on guinea pigs.
2. Effect on experimental hepatitis
Yinchenhao Decoction, Yinchenhao and Chinese wolfberry rhubarb decoction can reduce the mortality of carbon tetrachloride poisoning hepatitis in mice, Yinchen's aqueous extract and refined concentrated infusion, and toxic hepatitis for antimony tetrachloride The choleretic effect of dogs is more significant than that of normal dogs. Yinchen decoction and Yinchen volatile oil have no effect on serum transaminase in carbon tetrachloride toxic hepatitis rabbits, but the latter can increase the food intake of hepatitis rabbits. Hepatitis mice did not improve their mortality and hepatocyte pathology.
Yinchenhao Decoction has promoted liver cell regeneration in rabbits.
3. Antipyretic and antimicrobial effects
Yinchenhaotang and Artemisia scoparia extract have antipyretic effects on artificial fever in rabbits. The volatile oils of Yinchen and its genus Artemisiatridentata and A.nova have obvious inhibitory effects on Staphylococcus aureus in vitro, against dysentery bacilli, hemolytic streptococcus, pneumococci, diphtheria, bovine and human tuberculosis. Bacillus and the like also have a certain inhibitory effect. The volatile oil of capillaris can inhibit the growth of skin pathogenic fungi in vitro, and its antifungal active ingredient is caprolactone.
4, antihypertensive effect
Both Yinzhi's water infusion and refined infusion have antihypertensive effect. 6,7-Dimethoxycoumarin intravenous injection and duodenal administration have antihypertensive effects on rats, cats, rabbits and dogs. The antihypertensive effect may be caused by the expansion of the central and visceral blood vessels; the coronary flow of the isolated ventricular fibrillation rabbits is significantly increased, and the rhythm contraction is restored; the cat and rabbit electrocardiogram are observed. There may be transient atrioventricular block and indoor conduction block.
5, diuretic effect
Yinchen's aqueous extract, refined concentrated infusion and 6,7-dimethoxycoumarin have a diuretic effect on dogs. The volatile oil of Yinchen can increase the urine output of rabbits with toxic hepatitis, and the urine color changes from yellow to yellow. .
6, other effects
Yinchen decoction 3 g / kg for rabbits with experimental atherosclerosis, serum cholesterol and β-lipoprotein decreased after 2 to 3 weeks of administration, and the β/γ ratio was lower than that of the control group, but C The /P value was higher than that of the control group, and it showed protective effects on the lesions of the aortic arch and visceral fat deposition. Yinchen decoction has anti-Ehrlich ascites cancer in the test tube, and is effective only for the mice that are inoculated with Ehrlich ascites cancer. The emulsion of the genus Artemisiacaerulescens L. oil of the genus Yinchen can cause epileptic seizures in mice, and its action site is in the cerebral cortex.
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