Shanghai Xinfan Bio-Invented New Gene Sequencing Technology Helps Rapid Diagnosis of Blood Cancer

Australian scientists have invented a new gene sequencing technology called "capture sequencing" that is much more accurate than existing methods. It is like a microscope with multiples that can be used to fine-tune the genome and help diagnose blood cancer (leukemia) quickly.

上海信帆生物 澳发明新基因测序技术 有助快速诊断血癌

Australian scientists have invented a new gene sequencing technology that is much more accurate than existing methods. It is like a microscope with multiples that can be used to fine-tune the genome and help diagnose blood cancer (leukemia) quickly.

The technology, called Capture and Sequencing, was developed by researchers at the University of New South Wales and the Canadian Institute of Medicine and published in the new issue of the British Journal of Nature and Methodology.

The University of New South Wales recently announced that the technology can accurately measure the activity of multiple specific genes in a sample, even if the activity is very low. This sensitivity makes it very promising for biomedical research.

In addition to about 20,000 genes responsible for protein production, there are a large number of "non-coding genes" that do not make proteins, which play an important role in human development and brain function. However, many of these genes are very active and often only function in a few cells, making it difficult to study them in detail.

"Capture sequencing" technology can analyze genomes with higher precision, similar to taking photos with higher-pixel digital cameras, which can better represent the details that are difficult to detect in current sequencing technology and help to understand non-coding genes.

The technology can also be used for rapid detection of diseases such as blood cancer. The "fusion gene" composed of different genes is thought to be involved in some cancers, and there are about 200 fusion genes known to be associated with blood cancer. The current inspection technology can only detect fusion genes one by one, and "capture sequencing" can simultaneously find all 200 genes mentioned above, greatly speeding up the diagnosis and gaining time for treating patients.

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Manifold Filter

Manifold Filter, Spray guns contain filters that help provide a cleaner spray out of the gun tip. Here are some spray gun filter questions we`ve answered in the past, more than once.

1. What does a spray gun filter do?

The filter, which typically resides inside the handle of the gun, filters the paint one last time before it leaves the spray gun. The gun filter prevents debris from entering the tip. Preventing debris from entering the tip helps eliminate blockage, and therefore downtime, and keeps the spray surface clean.

2. Are there different types of filters? Which should I choose?

In general, the main difference in spray gun filters is in the screen size. You`ll want to choose a finer screen mesh for lacquers and fine finishes. A larger mesh can be used for latex paints.

3. How often do gun filters need to be replaced?

This can vary, too, depending on the amount of [trash", larger unwanted particulates, and the size of the mesh of your filter. Fine filters will need to be replaced more often. Why not clean them? Well, you can clean a filter, but generally these filters become so clogged over time that it is not worth the amount of work, and time, to clean them. It`s usually easiest to replace.

4. How often do gun filters need to be cleaned?

It is recommended that you clean the gun filter every time you clean your sprayer. This will give you the longest life for your spray gun filter. Eventually, though, you will have to replace the filter. Filters don`t wear out, as their made of stainless steel that prevents rust and corrosion, but they do accumulate trash and waste, despite the best efforts to keep them clean.

If you`re using an extremely fine mesh filter there is a chance that you could need to clean the filter during a job. The easiest way to tell a filter needs to be cleaned, during spraying, is the spray gun`s reversible tip begins to clog on a constant basis.

5. What would happen if you used the wrong filter for the tip?

It`s important to use the right filter mesh for the paint you`re spraying. If you use a wide mesh with a tip too small you`ll have a tip that constantly clogs. Using a fine mesh with a wide open tip you`d run into paint flow restriction. This can put unwanted stress on the sprayer, possibly reducing its lifespan.

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